Editor-in-Chief İlkay Küçükgüzel Associate Editor Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2019 , Vol 23 , Issue 6
Chemical analysis and in vitro antioxidant and anticholinesterase activities of essential oils and extracts from different parts of Erica manipuliflora
Çiğdem KUŞ1,Meltem TAŞ1,Selçuk KÜÇÜKAYDIN2,Gülsen TEL-ÇAYAN3,Mehmet Emin DURU1
1Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, Muğla 48000, Turkey
2Department of Medical Services and Techniques, Köyceğiz Vocational School of Health Services, Muğla Sıtkı Koçman University, Muğla 48000, Turkey
3Department of Chemistry and Chemical Processing Technologies, Muğla Vocational School, Muğla Sıtkı Koçman University, Muğla 48000, Turkey
DOI : 10.35333/jrp.2019.74 This study reports the chemical composition of essential oils and in vitro antioxidant and anticholinesterase activities of essential oils, hexane, ethyl acetate, methanol, and butanol extracts of aerial, flower and leaves parts of Erica manipuliflora. GC and GC/MS analyses were used for identification of essential oils. Totals of 47 compounds were detected in the essential oils of aerial, flower and leaves parts accounting for 99.99%, 99.88% and 99.97%, respectively. The major components of the aerial, flower and leaves parts of essential oils were Germacren D (14.76%, 15.55% and 13.58%), tau-cadinol (7.53%, 4.11% and 8.96%), caryophyllene oxide (3.92%, 5.17% and 8.55%), β-caryophyllene (7.24%, 5.97% and 7.73%), and α-terpineol (6.85%, 6.14% and 4.18%), respectively. The essential oils of aerial (34.49%) and leaves (37.01%) parts consisted of mainly sesquiterpene hydrocarbons whereas essential oil of flower part (42.58%) included monoterpenoids. The essential oils and extracts were screened for their antioxidant and anticholinesterase activities. The results of activities showed that extracts possessed the highest antioxidant activity while essential oils had the highest anticholinesterase activity. This finding supposes that E. manipuliflora may be considered as valuable natural source with antioxidant and anticholinesterase properties for food, cosmetic and pharmaceutical industries. Keywords : Erica manipuliflora; chemical composition; essential oil; extracts; different parts; antioxidant activity; anticholinesterase activity
Marmara University