Editor-in-Chief İlkay Küçükgüzel Associate Editor Aslı Türe Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 2017 , Vol 21 , Issue 3
Anatomy and Activity Studies of Pedicularis condensata
Burcu Şen Utsukarçi1,Bahar Gürdal2,Turgut Taşkın3,Mayram Tüysüz4, Çağla Bozkurt Güzel4,Selin Tufan1,Afife Mat1
1İstanbul Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul
2İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul
3Marmara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul
4İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İstanbul
DOI : 10.12991/marupj.311812 The genus Pedicularis comprises with 11 species, 2 of them are endemic, in Turkey. The Pedicularis species are known as "sormuk, sorma, sormuk otu". Its usage is not well known in folk medicine, though the usage as food because of its nectar is recorded in East-Anatolia. According to the published studies on Pedicularis condensata Bieb. till today, it is seen that this plant takes a place in patent, taken during the hair dye studies. Additionally, various investigations on the isolation and activity of Pedicularis (Kesgerotu) species are reported in literature. According to these, the Pedicularis species contain iridoids and phenylethanoid compounds as major components. It has demonstrated that, the iridoids has antioxidant, antimicrobial, antiinflamatory, immunomodulator activities etc. and the phenylethanoid compounds show antioxidant, antibacterial, antiviral as well as antiinflamatory, hepatoprotective activities etc. In view of the isolation studies, it is possible that Pedicularis condensata shows some of these activities. The anatomical and activity studies on this species were not done. In this paper, an anatomical study and the results of activity tests of the extracts, which were obtained using various methods and different solvents, were presented. The antioxidant and antimicrobial activities, possessed by various extracts (hexane, dichloromethane, methanol and methanol macerate), which were prepared from the aerial parts (collected in Trabzon) by maceration and Soxhlet extraction, were investigated. Keywords : Pedicularis condensata, plant anatomy, antimicrobial, antioxidant
Marmara University