Editor-in-Chief İlkay Küçükgüzel Associate Editor Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 2016 , Vol 20 , Issue 2
Synthesis and antiviral activity evaluation of some new cyclohexylidenehydrazide derivatives of 1,3-thiazole core
Nuray ULUSOY1, Erkan PEHLIVAN1, Zeynep HALAMOGLU1, Ayse KOCABALKANLI1
1Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 34116 Istanbul, Turkey DOI : 10.12991/mpj.20162019913 Six novel cyclohexylidenehydrazide derivatives carrying five membered heterocyclic ring, 1,3-thiazole were synthesized to investigate their antiviral (including anti-HIV) activity against diverse DNA and RNA viruses in CRFK, HeLa, HEL, MDCK, Vero and MT4 cell cultures. None of the compounds was found active against any of the DNA or RNA viruses at 100 μM. Keywords : 1,3-Thiazole, cyclohexylidenehydrazide, antiviral activity
Marmara University