Editor-in-Chief İlkay Küçükgüzel Associate Editor Aslı Türe Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2020 , Vol 24 , Issue 5
Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale
VinodKumar MUGADA1,Pujitha KONDRU2,Sai Navya MANDA2,Mahalakshmi VEGI2,Smruthi KAKADA2
1Department of Pharmacy Practice, Faculty of Pharmacy, Vignan Institute of Pharmaceutical Technology, Vizag, India
2Department of Pharmacy Practice, Pharm.D 5th year, Vignan Institute of Pharmaceutical Technology, Vizag, India
DOI : 10.35333/jrp.2020.231 Knee osteoarthritis causes physical, functional limitations and difficulty in performing activities of daily living and mobility. The study aimed to assess patient-relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. A descriptive cross-sectional study was conducted on 120 patients. KOOS scale contains five subscales: pain, symptom, activities of daily living, sports/recreation, and quality of life. Score zero indicates the worst possible knee problems, while score 100 indicates no knee problems. Non-parametric tests, multiple linear regression analysis, and correlation were calculated for the data. The level of significance was p<0.05 and p<0.01. The mean age group of patients was 54.58±10.73 years. There was a statistically significant association observed between pain and disease duration (p=0.031); symptom and gender, comorbidities, and body mass index (p=0.038, 0.022, and 0.017, respectively); activities of daily living and knee surgery (p=0.043); sports/recreation and knee involved, disease duration (p=0.031, 0.033, respectively); and knee-related quality of life and gender (p=0.011). Knee surgery was an independent predictor for pain (p=0.008) and activities of daily living (p=0.008). There was a severe problem with sports/recreation in the patients. The knee-related quality of life was moderate. Knee surgery was found to be a strong independent predictor for pain and activities of daily living. However, socioeconomic status influenced the knee surgery in our patients. Keywords : Pain; Symptom; activities of daily living; sports; quality of life; KOOS; knee osteoarthritis
Marmara University