Editor-in-Chief İlkay Küçükgüzel Associate Editor Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2019 , Vol 23 , Issue 4
Electrochemical detection of anticancer drug lumazine and DNA interaction by using carbon nanotube modified electrodes
Hakan KARADENİZ1,Ece EKSIN1,Arzum ERDEM1
1Faculty of Pharmacy, Analytical Chemistry Department, Ege University, 35100, Bornova, İzmir, TURKEY DOI : 10.12991/jrp.2019.176 The interaction of lumazine (LMZ) with dsDNA was investigated with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) by using disposable carbon nanotubes-modified pencil graphite electrode (CNTs-PGE). The passive adsorption process was used to modify the electrode surface by CNTs and then dsDNA was immobilized onto the modified PGEs. The performance of CNT-PGEs was studied by examining the optimum analytical conditions with DPV and then impedance method was performed to characterize the modification of CNTs onto the electrode surface. Keywords : Biosensor; carbon nanotubes; electrochemistry; lumazine
Marmara University