Editor-in-Chief İlkay Küçükgüzel Associate Editor Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 2013 , Vol 17 , Issue 2
Natural polymers: Best carriers for improving bioavailability of poorly water soluble drugs in solid dispersions
Sandip Sapkal, Mahesh Narkhede, Mukesh Babhulkar, Gautam Mehetre, Ashish Rathi
IBSS college of Pharmacy, Malkapur, Pharmaceutics, Mahartashtra, India DOI : 10.12991/201317375 Natural polymers and its modified forms can be used as best alternative for improving bioavailability of poorly water soluble drugs in solid dispersion. Most of the natural polymers are hydrophilic and having high swelling capacity. Recent trend towards the use of natural polymer demands the replacement of synthetic additives with natural ones. Many plant derived natural polymers are studied for use in solid dispersion systems, out of which natural gums, cyclodextrin and carbohydrate are most extensively studied and used. This review discusses about the majority of these natural polymers, its uses and some recent investigations about modification of natural polymer in solid dispersion systems. Keywords : Modified natural gum, carbohydrate, dissolution enhancement, solid dispersion
Marmara University