Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1989 , Vol 5 , Issue 1
Studies on formulation, pilot manufacturing and controlled release of micropellets containing antazoline
Kandemir Canefe,Cem Özyurt
In this study, first the pelletizing dish method was used to investigate the formulation of micropellets containing the active substance.

Antazoline was used as model substance and various pharmaceutical xualitiy control methods were applied to micropellets manufactured with formulas showing optimal properties.

Following this procedure, the micropellets carrying the active substance were coated with acrylic resins in order to obtain controlled release.

Release properties were examined by in-vitro experiments and with different kinetic calculations. As a result, micropellet formulations showing controlled release have been developed which can be useful guides for the pharmaceutical industry of our country. Keywords : Micropellets, pelletizing dish, antazoline micropellets, controlled release

Marmara University