Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1996 , Vol 12 , Issue 2
Urinary citrate excretion in patients with urolithiasis
Tülay Akçay,Dildar Konukoğlu ,Ali Rıza Kural
Urinary citrate excretion of of 31 healthy people and 67 patients with urolithiasis by colorimetric citrate lyase assay.

A statistically significant difference was detected between the healthy male (325± 75.9 mg/g Cr ) and female (453± 132 mg/g Cr) (p<0.05) and it was seen that mean urinary citrate excretion of patients (172.61± 89.27 mg/g Cr) was significantly lower than that of healthy people (391± 105.9 mg/g Cr) (p<0.001).

There was not a significant difference between the urinary citrate excretions of primer (180.07±90.5 mg/g Cr) and recurrent (172.2± 88.18 mg/g Cr) stone formers.

Therefore the decreased citrate excretion is an important factor of stone formation. Keywords : Citrate, Urolithiasis, Stones

Marmara University