Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1994 , Vol 10 , Issue 1
Synthesis of some substituted 1,3,4-thiadiazole derivatives
N.Nehir Gülerman,Sevim Rollas,Mert Ülgen
Treatment of 1- aroyl - 4- substituted thiosemicarbazides with concentrated sılphuric acid quickly leads to cyclization to stable 5- [p-{benzoylamino) phenyl] -2 - substituted amino-1,3,4- thiadiazoles in high yields at ambient temparature. The structures and purity of these compounds were confirmed using spectrometric and spectroscopic techniques ie UV, IR, MASS, together with their melting point and elemental analyses. Keywords :
Marmara University