Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1993 , Vol 9 , Issue 2
The level of G proteins in control and differentiated K562 cells
Bahire Küçükkaya,Beki Kan
Membranes were prepared from K562 cells grown in suspension culture and chemically induced to differentiate with hemin. Guanine nucleotide binding assays performed in these fractions showed a 150% increase in GTPγS binding activity of differentiated cell membranes with respect to the control groups. However, immonoblot analysis using specific antibodies indicated that there were no significant differences in the total amounts of G protein subunits between the two groups. Keywords :
Marmara University