Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1991 , Vol 7 , Issue 1
Synthesis and characterization of some new 2,4,6-trisubstituted N,N-dibenzylanilines
Mert Ülgen,J.W. Gorrod
The benzylation of certain ring substituted anilines were carried out in order to produce benzyl derivatives which were required as substrates for drug metabolism studies. The procedure employed gave rise to desired secondary anilines, but N,N-dibenzyl derivatives were obtained. Isolation and characterisation of these secondary products were carried out as they may also be used as substrates for future metabolic experiments, on microsomal C- and N-oxidation. This report contains the synthesis, purification and chemical characteristics of such isolated tertiary anilines. Keywords :
Marmara University