¹Department of Pharmacy Practice, Faculty of Pharmacy, Vignan Institute of Pharmaceutical Technology, Vizag, India
²Department of Pharmacy Practice, Pharm.D 5^th year, Vignan Institute of Pharmaceutical Technology, Vizag, India DOI : 10.35333/jrp.2020.231 Knee osteoarthritis causes physical, functional limitations and difficulty in performing activities of daily living and mobility. The study aimed to assess patient-relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. A descriptive cross-sectional study was conducted on 120 patients. KOOS scale contains five subscales: pain, symptom, activities of daily living, sports/recreation, and quality of life. Score zero indicates the worst possible knee problems, while score 100 indicates no knee problems. Non-parametric tests, multiple linear regression analysis, and correlation were calculated for the data. The level of significance was p<0.05 and p<0.01. The mean age group of patients was 54.58±10.73 years. There was a statistically significant association observed between pain and disease duration (p=0.031); symptom and gender, comorbidities, and body mass index (p=0.038, 0.022, and 0.017, respectively); activities of daily living and knee surgery (p=0.043); sports/recreation and knee involved, disease duration (p=0.031, 0.033, respectively); and knee-related quality of life and gender (p=0.011). Knee surgery was an independent predictor for pain (p=0.008) and activities of daily living (p=0.008). There was a severe problem with sports/recreation in the patients. The knee-related quality of life was moderate. Knee surgery was found to be a strong independent predictor for pain and activities of daily living. However, socioeconomic status influenced the knee surgery in our patients. Keywords : Pain; Symptom; activities of daily living; sports; quality of life; KOOS; knee osteoarthritis