Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2020 , Vol 24 , Issue 2
Trace element analysis in some Salvia species by inductively coupled plasma-mass spectrometry (ICP-MS) and chemometric approach
Zeki TUNAY1,İsmail YENER2,Elif VARHAN ORAL2,Aslı Barla DEMIRKOZ3,Özge TOKUL-ÖLMEZ5,Mehmet FIRAT6,Mehmet ÖZTÜRK5,Işıl AYDIN2,Fırat AYDIN7,Abdulselam ERTAŞ8
1Dicle University Science and Technology Application and Research Center (DUBTAM), TR-21280 Diyarbakır, Turkey
2Department of Analytical Chemistry, Faculty of Pharmacy, Dicle University, TR-21280 Diyarbakır, Turkey
3AROMSA A.S, R&D Center, GOSB Ihsan Dede Cad. 700. Sk. No: 704, TR-41480, Kocaeli, Turkey
4Department of Industrial Engineering, Faculty of Engineering, Haliç University, TR-34445, İstanbul, Turkey
5Department of Chemistry, Faculty Science, Muğla Sıtkı Koçman University, TR-48121 Muğla, Turkey
6Department of Biology, Faculty of Education, Yüzüncü Yıl University, TR-65080 Van, Turkey
7Department of Chemistry, Faculty Science, Dicle University, TR-21280 Diyarbakır, Turkey
8Department of Pharmacognosy, Faculty of Pharmacy, Dicle University, TR-21280 Diyarbakır, Turkey DOI : 10.35333/jrp.2020.146 In this study, the stems, leaves, flowers, roots and mixed all parts of five Salvia species were analyzed for their trace element (Li, Be, V, Cr, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Ag, Cd, Cs, Ba, Hg, Tl, Pb, and U) contents using ICP-MS. The seeds, roots leaves, flowers, and mixed parts of each species were digested by concentrated nitric acid and hydrogen peroxide in a microwave by before ICP-MS the analysis. The accuracy and precision of the method were evaluated by CRM 1573a Tomato Leaves. Trace element contents in different parts of each sample were compared. Concentration of toxic elements (As, Cd, Hg and Pb) were lower than those declared by WHO, except Cr content. Cr content in the root sections of Salvia suffruticosa (SFR), S. hydrangea (SHR), S. trichoclada (STR), S. xanthocheila (SXR), leaf samples of S. kronenburgii (SKL) and S. xanthocheila (SXL). also the Cr content in the leaf sections of Salvia kronenburgii (SKL) Salvia xanthocheila (SXL) was found high. When consider the daily metal (Zn, Cu, Sr, Ba and Ni ) needs It was concluded that these Salvia species can be nutritive sources. In addition, Salvia samples were classified by utilizing chemometric techniques such as Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA). While the first two main components explained 55.30% of the total variance, the first six main components explained 89.60% of total variance. Keywords : Salvia, trace element, ICP-MS, PCA
Marmara University