Editor-in-Chief
Hatice Kübra Elçioğlu
Vice Editors
Levent Kabasakal
Esra Tatar
Online ISSN
2630-6344
Publisher
Marmara University
Frequency
Bimonthly (Six issues / year)
Abbreviation
J.Res.Pharm.
Former Name
Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal
1989 , Vol 5 , Issue 1
Fluorodensitometric determination of capsaicinas its dansyl derivative
A fluorodensitometric method was developed for the determination of capsaicin by means of the derivative formed with dansyl chloride. The reaction proceeded quantitatively at room temperature in 20 min and in acetone-Na2CO3(3:1) system when the molar ratio of reagent to capsaicin was 8. After TLC separation of reaction product on silica-gel plate the fluorescence intensity of the derivative was measured at 525 nm, using 366 nm excitation filter. The fluorencence intensity is linear over the concentration range of 5-500 ng capsaicin/spot. The proposed method was applied to determination of capsaicin in capsicum fructus. The range of recovery from Capsicum fructus is 98.8-100.6%.
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