Editor-in-Chief
Hatice Kübra Elçioğlu
Vice Editors
Levent Kabasakal
Esra Tatar
Online ISSN
2630-6344
Publisher
Marmara University
Frequency
Bimonthly (Six issues / year)
Abbreviation
J.Res.Pharm.
Former Name
Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal
1989 , Vol 5 , Issue 1
Studies on formulation, pilot manufacturing and controlled release of micropellets containing antazoline
In this study, first the pelletizing dish method was used to investigate the formulation of micropellets containing the active substance.Antazoline was used as model substance and various pharmaceutical xualitiy control methods were applied to micropellets manufactured with formulas showing optimal properties.
Following this procedure, the micropellets carrying the active substance were coated with acrylic resins in order to obtain controlled release.
Release properties were examined by in-vitro experiments and with different kinetic calculations. As a result, micropellet formulations showing controlled release have been developed which can be useful guides for the pharmaceutical industry of our country.
Keywords : Micropellets, pelletizing dish, antazoline micropellets, controlled release