Editor-in-Chief
Hatice Kübra Elçioğlu
Vice Editors
Levent Kabasakal
Esra Tatar
Online ISSN
2630-6344
Publisher
Marmara University
Frequency
Bimonthly (Six issues / year)
Abbreviation
J.Res.Pharm.
Former Name
Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal
2013 , Vol 17 , Issue 2
Natural polymers: Best carriers for improving bioavailability of poorly water soluble drugs in solid dispersions
IBSS college of Pharmacy, Malkapur, Pharmaceutics, Mahartashtra, India
DOI :
10.12991/201317375
Natural polymers and its modified forms can be used as best alternative for improving bioavailability
of poorly water soluble drugs in solid dispersion. Most of the natural polymers
are hydrophilic and having high swelling capacity. Recent trend towards the use of natural
polymer demands the replacement of synthetic additives with natural ones. Many plant derived
natural polymers are studied for use in solid dispersion systems, out of which natural
gums, cyclodextrin and carbohydrate are most extensively studied and used. This review
discusses about the majority of these natural polymers, its uses and some recent investigations
about modification of natural polymer in solid dispersion systems.
Keywords :
Modified natural gum, carbohydrate, dissolution enhancement, solid dispersion