¹Scientific Center for Innovative Technologies and Research, Kazakhstan
²Department of Healthcare of Zhambyl region in Kazakhstan
³Facultad de Medicina, Universidad Autónoma de Guerrero, Laboratorio de Investigación Clínica, Acapulco, Guerrero, México DOI : 10.29228/jrp.2022.00 The field of nutrigenomics has gained considerable limelight and interdisciplinary researchers have started to realize its significance as a goldmine for the discovery of pathways that are important as dietary targets. Emerging evidence has provided wealth of exciting proof-of-concept studies highlighting an important role in the elucidation of oncogenic signaling cascades that can be pharmacologically targeted by dietary agents, whole extracts and isolated compounds for the inhibition/prevention of carcinogenesis and metastasis. In this review, we have critically analyzed some of the mechanistic animal models studies which have rationally propelled the field in a frontward direction. We also provide an overview of the fruits-mediated anti-metastatic effects in metastasis models that highlight how nutrigenomics may be combined with pharmacological therapies for synergistic effects, potentially ushering a path towards precision nutrition for cancer. Keywords : Cancer; Nutrigenomics; Metastasis; Cell signaling; Apoptosis