¹Department of Dentistry, Faculty of Medical Sciences, Albanian University, Rruga e Durresit, AL1001, Tirana, Albania
²Department of Pharmacy, Faculty of Medical Sciences, Albanian University, Rruga e Durresit, AL1001,Tirana, Albania
³Department of Pharmacy, University of Medicine, Rruga e Dibres Nr. 371, AL1005, Tirana, Albania DOI : 10.29228/jrp.2022.00 Honey is one of the oldest natural compounds that come from ancient times to nowadays with health benefits. It has been used for the treatment of several diseases, but its role in oral health faces real skepticism due to the high concentration of carbohydrates in its composition. Many studies over the years have confirmed several pharmacological activities such as antioxidant, antibacterial, antihistaminic, etc. It is composed of different chemical compounds like carbohydrates, proteins, amino acids, vitamins, minerals, organic acids, phenolic compounds, and volatile substances. Honey contains many enzymes such as invertase, catalase, glucose oxidase, and acid phosphorylase, as well as traces of vitamins B2, B4, B5, B6, B11, and vitamin C, minerals such as calcium, iron, zinc, potassium, magnesium. A promising challenge is the use of honey as a targeting product obtained from green synthesis, with high-efficiency thanks to nanotechnology. This study aims to investigate the potential benefits of honey in oral health, leveraging its diverse biological activity like antimicrobial, and antioxidant effects. Additionally, our scope was to provide scientific evidence supporting the use of honey in dentistry, emphasizing its broader health benefits and novel applications in oral health care. Keywords : Honey; biological activity; oral health; dental caries; periodontitis