¹Deaprtment of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
²Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India
³Department of Pharmaceutics, Maliba Pharmacy College, UKA Tarsadia University, India
⁴Department of Pharmacognosy, Maliba Pharmacy College, UKA Tarsadia University, India DOI : 10.29228/jrp.536 According to Persian Medicine (PM), the primary qualities of herbs or their nature play a crucial role in their medical applications. Objective: This library-based study aimed to determine the association between plants’ tannin content and their cold and dry nature considered by ancient Persian philosophers. Methods: plants with cold and dry nature were extracted from monographs of Makhzan al-Adviyah and Tuhfat ul-Momineen, the latest and the most comprehensive ancient Persian pharmacopeias. For determining the mentioned pants tannin content, scientific search engines were explored. Results: the results of this study were shown in a Table 1 containing 53 herbs with cold and dry temperament, providing their Persian and scientific names and medicinal parts, belonging to thirty-six botanical families. Table 1 also presented the tannin content of herbs (hydrolysable and condensed tannins). Five out of fifty-three herbs were not backed with any scientific evidence to contain tannins. Among the botanical families, Solanaceae, Fabaceae, Rosaceae, and Poaceae were repeated several times in which tannins could be assumed as their chemotaxonomic markers. Thus, temperaments could predict chemotaxonomic markers of herbs. Furthermore, there was an overlap between medical applications of herbs with their cold and dry nature and their pharmacological activities, including anti-hemorrhoid, anti-helminthic, anti-diarrhea, buccal ulceration, and gastro-protective. Tannincontaining plants with cold and dry nature could be explored to indicate unidentified pharmacological activities. Conclusion: Philosophical approaches of PM could be the fundamentals of medical discoveries to fill the gap between traditional and conventional medicine regrading chemotaxonomy markers, phytochemical studies, and pharmacological activities of herbs. Keywords : Conventional medicine; nature; Persian traditional medicine; tannin; temperament; traditional medicine