Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2023 , Vol 27 , Issue Supp.
GROUNDBREAKING DELIVERY SYSTEMS: LIPOSOME -MICROBUBBLES COMPLEXES
Pankaj DWIVEDI1
1University of Health Science and Pharmacy in Saint Louis, USA DOI : 10.29228/jrp.507 Liposome-microbubble (LMBs) complexes are a type of drug transport system that is being advanced for most cancers therapy. LMBs is a singular technique inside the area of targeted chemotherapy that combines the benefits of liposomes and microbubbles.

Where liposomes are small, spherical structures with lipid bilayer which can encapsulate drugs, microbubbles are gas-stuffed lipidic system which are clinically used for ultrasound imaging. While those two systems are mixed, the resulting LMBs can target and supply therapeutics without delay to cancer cells. This method has the capability to improve the efficacy of cancer healing procedures and decrease facet effects through focusing the transport of the drugs to the most cancerous cells. Moreover, using ultrasound imaging to guide the delivery of the complexes can help enhance the accuracy and specificity of the treatment.

LMBs are created with the aid of encapsulating therapeutics within liposomes and then coating these liposomes as a layer to microbubbles. This aggregate results in a hybrid drug delivery system that lets in for focused and controlled launch of the therapeutic sellers on the site of disease.

The microbubbles serve as a comparison agent, allowing visualization of the LMBs for the duration of ultrasound imaging, which lets in real-time tracking of their movement and distribution within the body. This permits for precise focus on the therapeutic sellers to the diseased tissue, reducing the facet effects associated with traditional chemotherapy and increasing the healing efficacy of the treatment.

LMB technology has proven promising effects in preclinical research and is currently being examined in scientific trials for the treatment of various forms of cancer, which include solid tumors and hematologic malignancies. in addition, this generation also can be used to supply healing dealers to different diseases, along with cardiovascular and inflammatory problems.

In conclusion, the liposome-microbubble era is a promising approach within the discipline of focused chemotherapy, presenting the potential for improved efficacy and decreased side results compared to traditional chemotherapy techniques. Keywords : Liposome-microbubble complexes, drug transport systems, targeted chemotherapy

Marmara University