¹Department of Pharmaceutical Toxicology, School of Pharmacy, Istanbul Medipol University, Istanbul, Türkiye
²Department of Pharmacology, Veterinary Drug Residue Laboratory, Pendik Veterinary Control Institute, Istanbul, Türkiye
³Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istanbul University, Istanbul, Türkiye
⁴Department of Pharmacology, Doping Control Laboratory, Pendik Veterinary Control Institute, Istanbul, Türkiye
⁵Department of Pediatric Neurology, Faculty of Medical, Istanbul University, Istanbul, Türkiye DOI : 10.29228/jrp.487 Human biomonitoring (HBM) studies are carried out to examine the effects of environmental pollutants on human health and to identify risks to public health, with the increasing awareness of environmental pollution around the world. The aim of our study is to determine the level of trace elements and to perform preliminary human biomonitoring of a healthy urban population in Türkiye. For this purpose, healthy individuals living in the same region and not known to have occupational or any other exposures were included in the study. Element levels from serum/blood of volunteers were determined. In this study, Inductively Coupled Plasma Mass Spectrometry (ICP-MS) was used to analyze in order to determine the multi elements in a more precise way with an improved analytical quality of results. According to our study’s results, Mn and As (p<0.05) were found statistically significant with age. Smoking had an effect on Cd levels (p<0.01) and there were significant differences between males and females for only Zn (p<0.05). The results of our study provided more information on the reference values of Zn, Cu, Mn, Cd and As elements of the Turkish population and reported the influences of age, gender and smoking habits on trace element profiles. Keywords : Biomonitoring; trace elements; ICP-MS; blood; serum