Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Marmara Pharmaceutical Journal 1992 , Vol 8 , Issue 2
The investigation on the antibacterial and antifungal effects of some volatile oils
Taner Dortunç,Adile Çevikbaş
In this study, essential oils of 9 plants (Montha piperita, M. spicata, o. onites, O. heracleoticum, S.sclarea, S. crypthantha, S. triloba, M. officinalis and L.nobilis) were investigated for their antimicrobial activities against B.subtilis, B. cereus, M. luterus, S. aureus, E. hirae, P. aeruginosa, K. pneumoniae, P.mirabilis, E. coli, A.niger, A.versicolor, A. parasiticus, A.fumigatus, A.candidus, A.ochraceus, P. chyrsogenum, P. crustatum, P. aurentiogrisum, Fusarium spp. and C. chartarum. Activities were determined by double- layer agar diffusion method. Essential oil of O.onites was active against all the bacteria except P. aureginosa and molds tested and it displayed the highest antimicrobial activity amongst all the essential oils. Essential oil combinations of M. piperita, plus M.spicata and O. onites plus O. heracloticum were tested against all the bacterial and mold strains to detect the interactions between the components of the essential oils.

No significant effect was observed with the first combination; however, slight increases in antimicrobial activity were detected in the second one.

Tube dilution method was used to determine the MIC and MBC/MFC valules of the essential oil of O. onites for B. subtilis, S. aureus, P. aeruginosa, E coli, A. niger A. candidus, P. chrysogenum and Fusarium spp. P. aeruginosa and P. chyrsogenum were found to be the most susceptible microorganisms to the essential oil of O. onites Keywords :

Marmara University