Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2022 , Vol 26 , Issue 6
Cornelian Cherry (Cornus mas L.): Insight into its Phytochemistry and Bioactivity
Can Kerem ÇEVİK1,Kevser TABAN AKÇA1,İpek SUNTAR1
1Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler 06330 Ankara, Türkiye DOI : 10.29228/jrp.245 Cornus mas L. (Cornelian cherry) (family Cornaceae) is one of the important medicinal plants with a rich phytochemical profile. It is an ornamental plant with edible fruits possessing therapeutic and nutritional values. The fruits have been used in folk medicine since ancient times. They are red-colored, pear-shaped, oval, and sour taste and are often used in the form of beverages, marmalade, and jams, as well as utilized in the cosmetic industry. Phytochemicals reported for C. mas are phenolic acids, flavonoids, organic acids, anthocyanins, tannins, fatty acids, iridoids, and carotenoids. Especially, the fruits are rich in anthocyanins, vitamin C, and phenolic compounds. The extracts and compounds from C. mas have been investigated for antimicrobial, cytotoxic, anti-inflammatory, antioxidant, antiatherosclerotic, antihyperlipidemic, antidiabetic, anti-colitis, neuroprotective, hepatoprotective, cardioprotective, and nephroprotective activities. The objective of the present review is to summarize the recent studies on the phytoconstituents of C. mas and their biological effects. Keywords : Cornus mas; Cornaceae; phytochemistry; biological activity; traditional medicine; natural products
Marmara University