Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy 2022 , Vol 26 , Issue 4
Antioxidant, Antityrosinase Activities and Composition of Essential Oils Obtained from Roots and Fruits of Ferulago longistylis Boiss
Mine KÜRKÇÜOĞLU1,Hale Gamze AĞALAR1,Burak TEMİZ1,Ahmet DURAN2,Mehmet Yavuz PAKSOY3,Kemal Hüsnü Can BAŞER4
1Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470, Eskisehir, Turkey
2Emeritus Professor, Department of Biology, Faculty of Science, Selçuk University, 42075, Konya, Turkey
3Department of Environmental Engineering, Faculty of Engineering, Munzur University, 62000, Tunceli, Turkey
4Department of Pharmacognosy, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus
DOI : 10.29228/jrp.176 This study was aimed to evaluate the potential uses of Ferulago longistylis Boiss. essential oils in cosmetic applications. The air dried roots and fruits were subjected to water distillation by using a Clevenger apparatus for 3 h. Both essential oils were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC/MS) systems, simultaneously. The essential oil yields of the fruits and roots were calculated as 4% and 0.91%, respectively. The major compounds were identified as 2,3,6-trimethylbenzaldehyde (29.5%), cis-chrysanthenyl acetate (15.2%), (Z)-β-ocimene (12.4%), α-pinene (12.0%) and myrcene (11.4%) in the fruit essential oil while the root essential oil was characterized with high content of α-pinene (90.5%). Both essential oils were evaluated for their potential antioxidant and antityrosinase activities. The both essential oils showed weak Trolox equivalent antioxidant capacity and DPPH radical scavenging activity. The fruit essential oil showed weak antityrosinase (%25 inhibition, 1 mg/mL) activity while the root essential oil was inactive. The results concluded that both essential oils were not promising in cosmetic applications. Keywords : Ferulago longistylis; α-pinene; 2,3,6-trimethylbenzaldehyde; antioxidant, antityrosinase
Marmara University