Editor-in-Chief Hatice Kübra Elçioğlu Vice Editors Levent Kabasakal Esra Tatar Online ISSN 2630-6344 Publisher Marmara University Frequency Bimonthly (Six issues / year) Abbreviation J.Res.Pharm. Former Name Marmara Pharmaceutical Journal
Journal of Research in Pharmacy Articles in Press
Preparation of compounded products in pharmacies and compounding-magistral pharmacy, personalized medicine in Türkiye and Spain
Erol Eli SİMSOLO1,Ahmet Nezihi PEKCAN1,Zeki Erdinç ÜLKER2,Hilmi BAKIR6,Ayşe Nilhan ATSÜ7,İsmail ASLAN8
1Department of Pharmaceutical Technology, Faculty of Pharmacy, Ege University, Bornova, İzmir, Türkiye
2Turkish Magistral Pharmacist’s Society, Sultan Mesud Mh. İstanbul St. Pekcan Apt. 82/1 42050, Karatay, Konya, Türkiye
3Rey Pharmacy, Onur Mh, 7371/2 Sk, No:26/A Gümüşpala, Bayraklı, İzmir, Türkiye
4Pekcan Pharmacy, Kuzgunkavak, İstanbul St. No:82/A, 42050 Karatay, Konya, Türkiye
5Ülker Pharmacy, Yenibaraj Mh, Hacı Ömer Sabancı St. 23 Seyhan, Adana, Türkiye
6Vocational School of Health Sciences, Uskudar University, İstanbul, Türkiye
7Department of Hair Care & Beauty, Vocational School, İstanbul Kent University, İstanbul Türkiye
8Department of Pharmaceutical Technology, Hamidiye Faculty of Pharmacy, University of Health Sciences Türkiye, Tıbbiye St., No:38, Üsküdar, İstanbul, Türkiye
9SFA R&D Private Health Services, Teknopark Blv, No:1 3A Z01, Teknopark Istanbul, Pendik, Istanbul, Türkiye
DOI : 10.29228/jrp.894 The pharmacist is the only individual authorised to prepare medicines as a result of the training they have received. The pharmacy profession is one of the few that will not accept mistakes in terms of human life and health. Even the smallest mistake can lead to irreversible consequences such as non-recovery, disability and death. In the event of such a situation, every sensitive pharmacist will undoubtedly face a great deal of conscientious responsibility. In order to avoid such a situation, it is necessary to be aware of the developments in the profession and to exercise caution when providing services. It is also important to avoid leaving work to others and to strive to avoid making any mistakes. Personalised medicines prepared by a pharmacist in a pharmacy laboratory according to a doctor's prescription, packaged and labelled, and presented to the patient are known as magistral products. These are formulations that are prescribed and prepared individually, with the doses of the active substance determined by the physician in terms of volume or weight according to the degree of the disease present in the patient. In the context of personalised therapies globally, the importance of compounding products is increasing daily, and the rules and regulations governing the preparation of compounding products vary from country to country.

This review study examines the laws, regulations, and rules applicable in Türkiye and Spain for the preparation of compounding products. It also considers the future of compounding pharmacy. Keywords : Compounded Products; Compounding Pharmacy; Magistral; i.v. Nutrition; Hormon Replacement Therapy; Personalized Medicine; Pharmacies in Türkiye; Spain

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